Something that is frequently encountered with a variety of strains is the difference in effects at differing doses. Although this varies depending upon the strain and where you buy kratom, typically, lower doses are relatively more stimulating than higher doses; while the cause of this is not well known, it likely has to do with the sedation curve of 7-hydroxymitragynine.

 

For anyone inexperienced with kratom, it is essential to know about the philosophy, theory and advice regarding kratom dosage.